Inverse Problem in Mechanics-based Cancer Detection

This project aims to develop an experimental framework for measuring mechanical behaviours of human or animal tissue, in which a stiff cancerous nodule resides, and using a computational method to detect the existence of the cancer.

The hypothesis is that, since most soft tissue cancers are stiffer than their healthy counterpart, the existence of the cancerous nodules in healthy tissue would lead to an 'abnormal touch' when the whole tissue is being mechanically deformed. Such mechanical 'feedback' could be used to identify the existence, and even the extent, of the nodule that cannot be seen on the surface.

Potential work include developing a mechanical measurement protocol (both quasi-static and dynamic) to measure the surface response of a soft tissue sample subject to mechanical forces/displacements. An optimisation-based inverse analysis strategy is needed to analyse the measurement data for cancer nodule detection.

Students who are interested in this project are encouraged to contact the supervisor for discussion.

Other Comments: 

Students who are interested in this project are encouraged to contact the supervisor for discussion

Supervisor name: 
Dr Yuhang Chen
Supervisor and Deputy email addresses: 
y.chen@hw.ac.uk

Related MSc programmes: