Your Chemistry has got Potential: Highly reactive intermediates without the “bang”.

Synthetic organic electrochemistry has its roots in the classic work of Faraday and Kolbe on the electrolysis of aliphatic carboxylic acids. Although a large number of transformations have been developed since then, many of which have been successfully applied in various industrial processes, the potential of preparative organic electrochemistry remains underestimated. However, the growing impetus to find greener and more cost-effective alternatives to traditional synthetic methods has recently led to the development of novel electrosynthetic methods.

In this talk we will present new, safe, green, affordable and efficient ways to generate highly reactive organic intermediates such as iso(thio)cyanates, isocyanides, orthoesters or even diazo compounds! We will also discuss their scale-up using flow electrosynthesis and demonstrate their real-world application in the pharmaceutical industry by reviewing case studies carried out with GSK, AstraZeneca and Johnson & Johnson.