Electrochemical Biosensor technologies for early point-of-care disease diagnostics

Circulating biomarkers provide useful indicators of biological processes in the human body, and their concentrations in biofluids have been used for clinical risk assessment, diagnosis, prognosis, and monitoring of therapeutic outcomes. Abnormal concentrations of circulating biomarkers are associated with health conditions. The key challenge for early diagnostics is for the rapid detection of low concentrations of circulating biomarkers in small sample volumes, typically in a complex mixture with large background noise. Electrochemical detection is a promising tool to detect the levels of circulating biomarkers in biofluids. Additionally, electrochemical sensors enable high throughput and rapid analysis of such biomarkers in bodily fluids for diagnostic and therapeutic applications. This talk will highlight some of our recent inter-disciplinary research in the field of electrochemical biosensors.