The development of microbubble theranostics using the Atomic Force Microscope
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The development of microbubble theranostics using the Atomic Force Microscope
Wed, 10/04/2013 - 14:30 to 15:30
Location:
Speaker:
Dr Vassilis Sboros
Affiliation:
Heriot-Watt University
Synopsis:
Atomic force microscopy (AFM) is a powerful mechanical nanosensor with force resolution in the order of piconewtons that is introduced in the last 25 years in biological research.
We used this technology to characterise and aid the development of microbubbles (MBs) as a targeted theranostics system. MBs are currently in use in the clinic as ultrasound contrast agents. The AFM can provide accurate assessment of viscoelasticity, structure and ligand performance and distribution.