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Radiation pressure, the force exerted by photons, has applications in cooling atoms, propelling spacecraft using solar sails and in microscopic particle trapping and manipulation. In this talk I will describe optical trapping and discuss single beam optical traps (optical tweezers), optical fibre traps and waveguide traps. Optical tweezers make use of a laser beam that is tightly focused by a high numerical aperture, enabling contactless particle manipulation in three dimensions. I’ll describe work carried out over the last year and a half towards developing 3D particle manipulation that does not require a laser beam to be directed through a high numerical aperture microscope objective. We are aiming to create ‘optical tweezers on a chip‘ using novel optical fibres so that optical tweezing of single cells can be easily realised under any microscope.